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Fetal Bovine Replacement Sera

Fetal bovine sera alternatives suitable for a variety of cell culture-related research and educational purposes.
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1

Cytiva HyClone™ FetalClone™ III Serum (U.S.)

Designed for fibroblast applications, supplement cell culture growth with U.S.-sourced HyClone™ FetalClone™ III Serum, the most widely applicable fetal bovine serum (FBS) alternative.

IgG levels Typically less than 2 μg/mL
USDA Safety Testing Included USDA Inspected
Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2 to 8°C.
Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected No
Product Type FBS Replacement Serum
Endotoxin Concentration ≤ 10 EU/mL
Certifications/Compliance Manufactured in cGMP (21 CFR 820) compliant and ISO9001 certified facilities
Sterility Sterile
Country of Origin United States
Product Line HyClone
Hemoglobin Concentration ≤ 20 mg/dL
2

Cytiva HyClone™ Bovine Growth Serum (U.S.)

Support cell culture growth with U.S.-sourced HyClone™ Bovine Growth Serum, a superior performing fetal bovine serum (FBS) replacement, consisting of bovine calf serum supplemented with chemically-defined components.

Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2° to 8°C.
Sterilization Method Sequential-filtered, 100 nm
Product Type Bovine Growth Serum
Quantity 500 mL
Endotoxin Concentration ≤ 10 EU/mL
Sterility Sterile
Hemoglobin Concentration ≤ 10 mg/dL
3

Cytiva HyClone™ FetalClone™ I Serum (U.S.)

Optimized for growth of hybridomas, supplement cell culture growth with U.S.-sourced HyClone™ FetalClone™ I Serum, a fetal bovine serum (FBS) alternative containing comparable IgG levels to those found in FBS.

USDA Safety Testing Included USDA Inspected
Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected No
Product Type FBS Replacement Serum
Endotoxin Concentration ≤ 10 EU/mL
Certifications/Compliance Manufactured in cGMP (21 CFR 820) compliant and ISO9001 certified facilities
Sterility Sterile
Country of Origin United States
Hemoglobin Concentration ≤ 20 mg/dL
5

Cytiva HyClone™ FetalClone™ II Serum (U.S.)

Optimized for the growth of CHO cells and derivatives.

IgG levels Typically less than 2 μg/mL
USDA Safety Testing Included USDA Inspected
Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2 to 8°C.
Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected No
Product Type FBS Replacement Serum
Additional Assays Gamma Globulin, Alkaline Phosphatase, Lactate Dehydrogenase, SGPT, SGOT, pH, Total Protein, Albumin, Blood Urea Nitrogen, Creatinine, Total Bilirubin, Sodium, Potassium, Calcium, Chloride, Inorganic Phosphorus, Osmolality, Iron, TIBC, Percent Iron Saturation, Glucose, IgG
Endotoxin Concentration ≤ 10 EU/mL
Sterility Sterile
Country of Origin United States
Product Line HyClone
Hemoglobin Concentration ≤ 20 mg/dL
6

Cytiva HyClone™ FetalClone™ II Serum (U.S.)

Developed for growth of CHO cells and derivatives, supplement cell culture growth with U.S.-sourced HyClone™ FetalClone™ II Serum, a fetal bovine serum (FBS) alternative, containing additional growth factors and supplements than basic formulations.

IgG levels Typically less than 2 μg/mL
USDA Safety Testing Included USDA Inspected
Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2° to 8°C.
Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected No
Heat Inactivated No
Product Type FBS Replacement Serum
Tested For Bluetongue,Bovine Adenovirus,Bovine Parvovirus,Bovine RSV,BVDV,Cytopathogenic Agents,Hemadsorbing Agents,Rabies Virus,Reovirus
Endotoxin Concentration ≤ 10 EU/mL
Sterility Sterile
Country of Origin United States
Hemoglobin Concentration ≤ 20 mg/dL
Processing None
8

Cytiva HyClone™ Fetal Clone I Serum

HyClone™ FetalClone™ I is a fetal bovine serum alternative optimised for the growth of hybridomas with comparable IgG levels to those found in FBS.

IgG levels Typically less than 2 μg/mL
USDA Safety Testing Included USDA Inspected
Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2° to 8°C.
Mycoplasma Detected No
Additional Assays Gamma Globulin, Alkaline Phosphatase, Lactate Dehydrogenase, SGPT, SGOT, pH, Total Protein, Albumin, Blood Urea Nitrogen, Creatinine, Total Bilirubin, Sodium, Potassium, Calcium, Chloride, Inorganic Phosphorus, Osmolality, Iron, TIBC, Percent Iron Saturation, Glucose, IgG
Tested For Bluetongue, Bovine Adenovirus, Bovine Parvovirus, Bovine RSV, BVDV, Cytopathogenic Agents, Hemadsorbing Agents, Rabies Virus, Reovirus
Quantity 500 mL
Endotoxin Concentration ≤ 10 EU/mL
Certifications/Compliance Manufactured in cGMP (21 CFR 820) compliant and ISO9001 certified facilities
Sterility Sterile
Country of Origin United States
Hemoglobin Concentration ≤ 20 mg/dL
9

Cytiva HyClone™ Bovine Growth Serum

A cost-effective alternative to Fetal Bovine Serum (FBS).

Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected Yes
Additional Assays Insulin, Gamma Globulin, Alkaline Phosphatase, Lactate Dehydrogenase, SGPT, SGOT, pH, Total Protein, Albumin, Blood Urea Nitrogen, Creatinine, Total Bilirubin, Sodium, Potassium, Calcium, Chloride, Phosphorus, Osmolality, Iron, TIBC, Percent Saturation, Glucose, IgG
Tested For Bovine Adenovirus, Bovine Parvovirus, Bovine RSV, BVDV, Cytopathogenic Agents, Hemadsorbing Agents, Rabies Virus, Reovirus
Endotoxin Concentration ≤ 10 EU/mL
Sterility Sterile
Hemoglobin Concentration ≤ 10 mg/dL
10

Cytiva Research Grade FBS, Irradiated and Heat Inactivated

Research grade Fetal Bovine Serum of South America Origin. Irradiated and Heat inactivated.

11

Cytiva HyClone™ FetalClone™ II Serum, US Origin

Offers the same basic formulation as FetalClone™ I with additional growth factors and supplements. Shows optimized growth of CHO cells and derivatives, with improved cell growth performance relative to fetal bovine serum (FBS).

13

Cytiva HyClone™ Cosmic Calf Serum (New Zealand origin)

A bovine calf serum fortified with iron and growth promoting factors for growing a broad spectrum of cell types.

USDA Safety Testing Included USDA Inspected
Content And Storage Sera should be stored at -10°C or lower. Once thawed, sera should be stored at 2° to 8°C.
Sterilization Method Sequential-filtered, 100 nm
Mycoplasma Detected Yes
Additional Assays Insulin,Gamma Globulin,Alkaline Phosphatase,Lactate Dehydrogenase,SGPT,SGOT,pH,Albumin,Blood Urea Nitrogen,Creatinine,Total Bilirubin,Sodium,Potassium,Calcium,Chloride,Inorganic Phosphorus,Iron,TIBC,Percent Saturation,Glucose,IgG
Tested For Bluetongue, Bovine Adenovirus, Bovine Parvovirus, Bovine RSV, BVDV, Cytopathogenic Agents, Hemadsorbing Agents, Rabies Virus, Reovirus
Quantity 1 L
Endotoxin Concentration ≤ 25 EU/mL
Sterility Sterile
Hemoglobin Concentration ≤ 25 mg/dL