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1,1-Dimethylbiguanide hydrochloride, Thermo Scientific™
1,1-Dimethylbiguanide hydrochloride (metformin hydrochloride, CAS # 115-70-4) is the salt of methylated biguanide, a compound exhibiting anti-hyperglycemic properties.
Brand: Thermo Scientific Alfa Aesar J63361.22
| Quantity | 100g |
|---|
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Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1
• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes
• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells
• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway
• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders
• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell
Chemische Identifikatoren
| C4H12ClN5 | |
| MFCD00012582 | |
| metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform | |
| hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride |
Spezifikation
| 1115-70-4 | |
| NH2C(=NH)NHC(=NH)N(CH3)2·HCl | |
| 100g | |
| metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform | |
| OETHQSJEHLVLGH-UHFFFAOYSA-N | |
| hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride | |
| 14219 | |
| 1,1-Dimethylbiguanide hydrochloride |
| C4H12ClN5 | |
| MFCD00012582 | |
| 14,5938 | |
| Soluble in water (50mg/ml),ethanol,and DMSO (50 mM). | |
| [H+].[Cl-].CN(C)C(=N)N=C(N)N | |
| 165.63 | |
| 165.62 |
Sicherheit und Handhabung
Produktidentifikator
Signalwort
Gefahrenkategorie
Gefahrenhinweis
Sicherheitshinweis
Ergänzende Informationen
- 1,1-Dimethylbiguanide hydrochloride
Signalwort
- Warning
Gefahrenkategorie
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
Gefahrenhinweis
- H302-Harmful if swallowed.
- H319-Causes serious eye irritation.
Sicherheitshinweis
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
Ergänzende Informationen
- MIXTURE LIST-Contains : Metformin hydrochloride
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