missing translation for 'onlineSavingsMsg'
Learn More

α-1-Antitrypsin Ab-1 Rabbit Polyclonal Antibody, Epredia™

Obtain accurate, reproducible results with Epredia™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody.

204.00€ - 429.00€

Specifications

Antigen alpha-1-Antitrypsin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
View More Specs

Products 3
Product Code Brand Form Quantity Price Quantity & Availability  
Product Code Brand Form Quantity Price Quantity & Availability  
12673247
View Documents Promotion Details
Epredia
RB-367-A1
Concentrated 500 μL
278.00€
500µL
View alternative products
Save Up to 
»
Estimated Shipment: 16-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
12663247
View Documents Promotion Details
Epredia
RB-367-A
Concentrated 1 mL
429.00€
1mL
View alternative products
Save Up to 
»
Estimated Shipment: 16-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
12603257
View Documents Promotion Details
Epredia
RB-367-R7
Ready-to-Use 7 mL
204.00€
7mL
View alternative products
Save Up to 
»
Estimated Shipment: 16-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Baboon, Monkey, Horse and Mink. Does not react with cow, kangaroo, pig, goat, sheep, cat, dog, guinea pig, mouse and chicken. Others not known.

Immunogen: Purified human serum α-1-AT

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

alpha-1-Antitrypsin Ab-1
Polyclonal
Rabbit
Enzyme
Purified human serum alpha-1-AT
Primary
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Baboon, Equine, Human, Mink
IgG
Videos
SDS
Documents

Documents

Product Certifications