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Thermo Scientific™ 2'-Fluoro-Bz-A Phosphoramidite, standard grade, serum vial bottle

Product Code. 17917122 Shop All Thermo Scientific Products
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Quantity:
1 g
Unit Size:
1g
Product Code. Quantity unitSize
17917122 1 g 1g
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Product Code. 17917122

Brand: Thermo Scientific™ 27160102

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Description

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C47H51FN7O7P
• Base: A
• Base Protection: Bz
• Formula weight: 875.92 g/mol
• HPLC purity: >98%
• 31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY

Specifications

For Use With (Equipment) AKTA Synthesizers, Applied Biosystems Synthesizers
Product Type 2in-Fluoro-Bz-A CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Adenosine (A)
Reagent Features 2in-Fluoro modified
Shipping Condition Room Temperature
Purity 98%
Quantity 1 g
Reagent Type Phosphoramidite
Grade Standard
Nucleic Acid Type RNA
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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