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Thermo Scientific™ 2'-OMe-Ac-C Phosphoramidite, standard grade, 28-400 finish bottle
2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis.
Brand: Thermo Scientific™ 27-1823-11
Additional Details : Weight : 0.05200kg
Description
2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.
Features:
• HPLC purity—≥98.0%; Sum of PIII impurities (140-152ppm) ≤0.5%
Specifications
| ≥98% | |
| MerMade Synthesizers | |
| 801.86 g/mol | |
| Store in freezer (at or below -20°C). | |
| 2in-OMe modified, Fast deprotection | |
| ≥98% (HPLC) | |
| Phosphoramidite | |
| RNA | |
| Powder | |
| C42H52N5O9P |
| Amber bottle (28-400 finish neck style) | |
| Base: C Base Protection: Ac |
|
| 2in-OMe-Ac-C CEP | |
| Cytidine (C) | |
| Room Temperature | |
| 1 g | |
| Standard | |
| Oligonucleotide synthesis | |
| 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | |
| 199593-09-4 |
For Research Use Only. Not for use in diagnostic procedures.