missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. Thermo Scientific Chemicals 4-Epitetracycline hydrochloride, can be used as a secondary standard

Thermo Scientific Chemicals 4-Epitetracycline hydrochloride, can be used as a secondary standard

Product Code. 10358320 Shop All Thermo Scientific Chemicals Products
Change view
Click to view available options
Quantity:
100 mg
500 mg
Packaging:
Glass bottle
Unit Size:
100mg
500mg
Product Code. Quantity Packaging unitSize
10358320 100 mg Glass bottle 100mg
10318370 500 mg Glass bottle 500mg
2 options
This item is not returnable. View return policy
Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Product Code. 10358320

Brand: Thermo Scientific Chemicals 233121000

Request Bulk or Custom Format

Please to purchase this item. Need a web account? Register with us today!

282.15 EUR valid until 2026-02-13
BEST PRICE on Promo! Use promo code "27988" to get your promotional price.
This item is not returnable. View return policy
Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Description

4-Epitetracycline hydrochloride, CAS # 23313-80-6, is a degradation product of tetracycline that shows antibiotic activity and can induce the protein biosynthesis inhibition.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 4-Epitetracycline hydrochloride is a metabolite derived from the degradation of tetracycline compounds and has been shown to display antibiotic activity
  • This compound blocks protein synthesis by binding to the 30S ribosomal subunit and interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex

Applications

  • This semi-synthesized compound derived from actinomycetes can decrease the activity of the Tet repressor effector in animal models
  • In vivo experiments revealed that 4-epitetracycline hydrochloride can induce a toxic response
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 23313-80-6
Molecular Formula C22H24N2O8·HCl
Molecular Weight (g/mol) 480.89
MDL Number MFCD00865028
InChI Key YCIHPQHVWDULOY-DXDJYCPMSA-N
Synonym 4-epitetracycline hydrochloride, epitetracycline hydrochloride, 4-epi-tetracycline hydrochloride, quatrimycin hydrochloride, epitetracycline hcl, unii-i7c3edl2yg, i7c3edl2yg, epitetracycline hydrochloride usp, 4r,4as,5as,6s,12as-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride
PubChem CID 54686189
IUPAC Name (4R,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl

Specifications

Melting Point 217.0°C
Color Yellow
Infrared Spectrum Authentic
Assay Percent Range 80% min. (as is,calculated)
Packaging Glass bottle
Quantity 100 mg
Specific Rotation − 322.00
Solubility Information Solubility in water: 100g/L. Other solubilities: 100g/L methanol
Formula Weight 480.89
Percent Purity ≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC)
Physical Form Fine Crystalline Powder
Chemical Name or Material 4-Epitetracycline hydrochloride
Show More Show Less

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • 4-Epitetracycline hydrochloride
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 2
 Hazard Statement
  • H361d-Suspected of damaging the unborn child.
  • H319-Causes serious eye irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
SDS

RUO – Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.