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Alfa Aesar™ 4-Methylumbelliferyl sulfate potassium salt, 98%

Substrate for sulfatase

Brand:  Alfa Aesar™ J66160.ME

Additional Details : CAS : 15220-11-8 Weight : 0.00050kg

Quantity 500mg

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Product Code. 15410517

  • 98.05€ / 500mg


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Description

Description

Applications
4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.

Solubility
Soluble in water at 5mg/ml

Notes
Excitation wavelength, 334 nm; emission wavelength, 370nm (pH 10.4). Reaction product: excitiation wavelength, 360nm; emission wavelength, 449nm
Specifications

Chemical Identifiers

15220-11-8
294.318
CSOCSPXOODWGLJ-UHFFFAOYSA-M
5044226
CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)[O-].[K+]
C10H7KO6S
MFCD00016970
4-methylumbelliferyl sulfate potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt, 4-methylumbelliferyl sulfate, potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt 1:1, potassium 4-methyl-2-oxo-2h-chromen-7-yl sulfate, potassium 4-methyl-2-oxochromen-7-yl sulfate, c10h7o6s.k, potassium 4-methyl-2-oxo-2h-1-benzopyran-7-yl sulphate, potassium 4-methylumbelliferyl sulfate
potassium;(4-methyl-2-oxochromen-7-yl) sulfate

Specifications

4-Methylumbelliferyl sulfate potassium salt
500mg
C10H7KO6S
3803203
Soluble in water at 5mg/ml
CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)[O-].[K+]
294.318
294.32
98%
White to Yellow
15220-11-8
MFCD00016970
4-methylumbelliferyl sulfate potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt, 4-methylumbelliferyl sulfate, potassium salt, 2h-1-benzopyran-2-one, 4-methyl-7-sulfooxy-, potassium salt 1:1, potassium 4-methyl-2-oxo-2h-chromen-7-yl sulfate, potassium 4-methyl-2-oxochromen-7-yl sulfate, c10h7o6s.k, potassium 4-methyl-2-oxo-2h-1-benzopyran-7-yl sulphate, potassium 4-methylumbelliferyl sulfate
CSOCSPXOODWGLJ-UHFFFAOYSA-M
potassium;(4-methyl-2-oxochromen-7-yl) sulfate
5044226
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