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  5. Tocris Bioscience™ A 1899

Tocris Bioscience™ A 1899
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Product Code. 18726426
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Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
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Product Code. 18726426

Brand: Tocris Bioscience™ 6972/5

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This item is not returnable. View return policy

Description

Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker

A 1899 is a potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) channel blocker (IC50 values are 7 nM and 70 nM for human TASK-1 and TASK-3 expressed in CHO cells, respectively). Displays >12.5-fold selectivity for TASK-1 and TASK-3 over other K+ channels (IC50 = 0.9 μM for K2P18.1/TRESK and >2 μM for all other channels tested). Binds within open channel pore.
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Specifications

Chemical Name or Material N-[(2,4-Difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1'-biphenyl]-2-carboxamide
CAS 498577-46-1
Quantity 5 mg
Molecular Formula C30H26F2N2O3
Purity 98%
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