missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ A 77-01

Tocris Bioscience™ A 77-01
GREENER_CHOICE

Product Code. 18719216
Click to view available options
Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
This item is not returnable. View return policy

Product Code. 18719216

Brand: Tocris Bioscience™ 6712/25

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent inhibitor of TGF-βRI

A 77-01 is a potent TGF-βRI (ALK-5) inhibitor (IC50 = 34 nM). Inhibits TGF-β transcriptional activation. Inhibits TGF-β-induced proliferation of lung epithelial cells and SMAD phosphorylation. Inhibits TGF-β-induced epithelial-to-mesenchymal transition (EMT). Also inhibitor of p38 MAPK. Likely active metabolite of A 83-01 (Cat. No. 2939).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]quinoline
CAS 607737-87-1
Quantity 25 mg
Molecular Formula C18H14N4
Formula Weight 286.33
Purity 98%
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.