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Tocris Bioscience™ (±)-ADX71743, >98%;

Description
Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro. Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant.
Specifications
Specifications
| Quantity | 10 mg |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Formula Weight | 269.34 |
| Purity | >98% |
| Chemical Name or Material | 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone |
Product Title
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