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anti-NUDT1 Matched Antibody Pair, Abnova

Product Code. 16182344
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Product Code. 16182344 Brand Abnova Brand No. H00004521AP11.1Set

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Description

Includes

Rabbit affinity purified polyclonal anti-NUDT1 (100μg); Mouse monoclonal anti-NUDT1, IgG2aκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.

ELISA

Specifications

Antigen NUDT1
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Unconjugated
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NUDT1.
Gene NUDT1
Gene Alias MTH1
Gene Symbols NUDT1
Host Species Mouse, Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Research Discipline Stem Cell Biology
Primary or Secondary Primary
Gene ID (Entrez) 4521
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-NUDT1 (100 μg) 2. Detection antibody: mouse monoclonal anti-NUDT1, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Isotype IgG2a
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