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anti-TDP1 Matched Antibody Pair, Abnova

Product Code. 16065249
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Product Code. 16065249 Brand Abnova Brand No. H00055775AP11.1Set

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Description

Includes

Rabbit MaxPab™ affinity purified polyclonal anti-TDP1 (100μg); Mouse monoclonal anti-TDP1, IgG1κ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

ELISA

Specifications

Antigen TDP1
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Unconjugated
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human TDP1.
Gene TDP1
Gene Alias FLJ11090/MGC104252
Gene Symbols TDP1
Host Species Mouse, Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Research Discipline Stem Cell Biology
Primary or Secondary Primary
Gene ID (Entrez) 55775
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-TDP1 (100 μg) 2. Detection antibody: mouse monoclonal anti-TDP1, IgG1 Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Isotype IgG1
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