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TFAM Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA124435

Additional Details : Weight : 0.01000kg

Product Code. 11571013

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Description

Description

PA1-24435 detects TFAM in Human samples. PA1-24435 has been successfully used in Western Blot procedures. By Western blot, PA1-24435 detects the ∽ 29 kDa TFAM protein. PA1-24435 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human TFAM. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Specifications

Specifications

TFAM
Polyclonal
Unconjugated
Q00059
TFAM
Synthetic peptide region of human TFAM.
50 μg
Primary
Human
Antibody
IgG
Western Blot
1 mg/mL
TFAM
MtTF1, TCF6, TCF6L1, TCF6L2, TCF6L3, mtTFA
Rabbit
Antigen affinity chromatography
RUO
7019
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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