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  5. Tocris™ AVE 1625

Tocris™ AVE 1625

Product Code. 18778876
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18778876

Brand: Tocris™ 6763/50

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This item is not returnable. View return policy

Description

Potent and selective CB1 receptor antagonist

AVE 1625 is a potent and selective CB1 receptor antagonist (IC50 values are 25 and 10 nM for human and rat CB1R, respectively). Exhibits >400-fold selectivity for CB1 over CB2 receptors. Attenuates Olanzapine (Cat. No. 4349) induced weight gain and food intake in rats with no effect on energy expenditure or motility. Also improves cognitive function in rodent schizophrenia models and ameliorates extrapyramidal side-effects of antipsychotics.
TRUSTED_SUSTAINABILITY

Specifications

Synonym Drinabant
Quantity 50 mg
Molecular Formula C23H20Cl2F2N2O2S
Formula Weight 497.38
Product Type Antagonist
Purity 98%
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