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Tocris Bioscience™ AZ 10397767

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.
Specifications
Specifications
| CAS | 333742-63-5 |
| Quantity | 50 mg |
| Target | Chemokine Receptor |
| Molecular Formula | C15H14ClFN4O2S2 |
| Formula Weight | 400.88g/mol |
| Product Type | Antagonist |
For Research Use Only
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