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BD Ac-IETD-CHO Caspase-8 Inhibitor

To study caspase-8 activity in apoptotic cell lysates

Brand:  BD 556554

Additional Details : Weight : 0.01000kg

Product Code. 15888728

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.


Description

Description

Members of caspase family have key roles in inflammation and mammalian apoptosis. Caspase-8 (FLICE/MACH-1) is a 55 kDa cytosolicprotein with homology to the CD95/Fas-associated signal transduction molecule, FADD, in addition to its homology with other caspases. Caspase-8 is activated early in apoptosis and is involved in the proteolysis and activation of pro-caspase-3

  • Synthetic tetrapeptide inhibitor of caspase-8
  • Contains the amino acid sequence that is the target for caspase-8 mediated proteolysis
  • Used as a negative (blocking) control
  • May be used in protease assays
  • Format: Purified

Fluorescence quantitation

Specifications

Specifications

Fluorescence quantitation
-20°C
55
Purified
Lyophilized in Dimethyl Sulfoxide
1 mg
Ac-IETD-CHO
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Research use only