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  4. ACROBiosystems Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (SPR verified)

ACROBiosystems Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (SPR verified)

Product Code. 17156311
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Quantity:
200 μg
25 μg
Unit Size:
200µg
25µg

Product Code. 17156311

Brand: ACROBiosystems FCMH82W725ug

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Description

Biotinylated Protein

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Biotinylated Human FCGRT&B2M Heterodimer Protein, His,Avitag, produced by co-expression of FCGRT and B2M, has a calculated MW of 34.2 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag

Specifications

Accession Number NP_001129491.1 (FCGRT) and NP_004039.1 (B2M)
Molecular Weight (g/mol) 34.2 kDa (FCGRT) and 11.7 kDa (B2M)
Quantity 25 μg
Source Biotinylated Human FCGRT&B2M; Heterodimer Protein, His,Avitag (FCM-H82W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)).
Immunogen Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
Storage Requirements -20°C
Gene Alias FcRn,FCGRT and B2M
Common Name FcRn (FCGRT and B2M)
Conjugate Precision Avi
Species Human
Protein Tag His Tag and Avi Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Biotin Labeled Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE
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