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  7. Bisindolylmaléimide 1, Thermo Scientific Chemicals

Bisindolylmaléimide 1, Thermo Scientific Chemicals

Product Code. 15485649
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25 mg
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Product Code. 15485649 Supplier Thermo Scientific Alfa Aesar Supplier No. J63401.MB
 Article restreint
Estimated Shipment: 14-12-2026
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Description

Inhibiteur très puissant et sélectif de la protéine kinase C

Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Le bisindolylmaléimide est utilisé comme inhibiteur hautement sélectif de toutes les isoformes de la PKC et comme inhibiteur léger de la GSK-3, utilisé pour sonder sélectivement les voies de transduction de l’hormone, de la cytokine et des signaux de facteur de croissance, un inhibiteur très puissant et sélectif de la protéine kinase C.

Solubilité
Insoluble dans l’eau.

Remarques
Conserver à l’écart des agents oxydants forts. Garder le récipient hermétiquement fermé. Stocker dans des conditions fraîches et sèches et dans des récipients bien scellés.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 133052-90-1
Formule moléculaire C25H24N4O2
Poids moléculaire (g/mol) 412.493
Numéro MDL MFCD00236428
Clé InChI QMGUOJYZJKLOLH-UHFFFAOYSA-N
Synonyme bisindolylmaleimide i, unii-l79h6n0v6c, rbt205 inhibitor, gö 6850, bisindolylmaleimide i gf 109203x, bim-1, chembl7463, 2-1-3-dimethylaminopropyl indol-3-yl-3-indol-3-yl maleimide, 3-1-3-dimethylamino propyl-1h-indol-3-yl-4-1h-indol-3-yl-1h-pyrrole-2,5-dione
CID PubChem 2396
ChEBI CHEBI:41072
Nom IUPAC 3-[1-[3-(diméthylamino)propyl]indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
SMILES CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54

Specifications

Nom chimique ou matériau Bisindolylmaleimide 1
Couleur Orange
Quantité 25 mg
Informations sur la solubilité Insoluble in water.
Poids de la formule 412.48
Forme physique Poudre cristalline

RUO – Research Use Only

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