Invitrogen™ Human Blimp-1 Synthetic Peptide

Description

Blimp-1 Synthetic Peptide, PEP-0433, from Invitrogen.

Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression. This peptide corresponds to 17 amino acids near the amino terminus of human Blimp-1.PEP-0433 can be used as a blocking peptide with polyclonal antibody PA5-20313.