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  6. Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Product Code. 11841245 Shop All Thermo Scientific Products
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Quantity:
50 mg
8 x 2 mg
10 x 2 mg
1 g
Unit Size:
1g
50mg
Pack of 10
Pack of 8
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Product Code. 11841245

Brand: Thermo Scientific™ 21585

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Description

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

Highlights:

  • Crosslink cell-surface proteins before cell lysis and immunoprecipitation
  • Identify receptor-ligand interactions by chemical crosslinking
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Identify near-neighbor protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Immobilize proteins onto amine-coated surfaces
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-to-Amine
Cleavable No
Formulation Bis(sulfosuccinimidyl) suberate; solid
Membrane Permeable No
Molecular Weight (g/mol) 572.43
PEGylated No
Sufficient For 28mL of typical 1X (1mM) reaction solution (total), or 8 separate uses
Spacer Arm Length 11.4Å
Quantity 8 x 2 mg
Solubility Water
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.

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