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CD144 (VE-cadherin), APC, clone: eBioBV13 (BV13), eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 17-1441-80
Informations supplémentaires : Poids : 0.25000kg
Description
Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.Applications Reported: This eBioBV13 (BV13) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioBV13 (BV13) antibody has been tested by flow cytometric analysis of the b.End3 cell line. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.Spécification
CD144 | |
Monoclonal | |
0.2mg/mL | |
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
P55284 | |
Cadherin-5, Vascular endothelial cadherin, VE-cadherin, 7B4 antigen, CD144 antigen, CDH5 | |
Rat | |
Affinity chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Murine |
Flow Cytometry | |
eBioBV13 (BV13) | |
APC | |
Cdh5 | |
Conjugated | |
Cdh5 | |
IgG1, kappa | |
25μg | |
Store at 2-8°C. Do not freeze. Light-sensitive material. | |
Primary | |
12562 |
For Research Use Only.