CD144 (VE-cadherin) Rat anti-Mouse, Biotin, Clone: eBioBV13 (BV13), eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 13-1441-80
Informations supplémentaires : Poids : 0.25000kg
DescriptionCell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered. This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Cadherin-5, Vascular endothelial cadherin, VE-cadherin, 7B4 antigen, CD144 antigen, CDH5|
|Flow Cytometry, Immunohistochemistry (Frozen), Western Blot|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.