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CD153 Rat anti-Mouse, PE, Clone: RM153, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 12-1531-81
Additional Details : Weight : 0.25000kg
Description
The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.Specifications
| CD153 | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
| P32972 | |
| CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; CD30-L; CD30L; CD30LG; TNFSF8; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8 | |
| Rat | |
| Affinity chromatography | |
| RUO | |
| Antibody | |
| Monoclonal | |
| Mouse |
| Flow Cytometry | |
| RM153 | |
| PE | |
| Tnfsf8 | |
| Liquid | |
| Tnfsf8 | |
| IgG2b, kappa | |
| 50 μg | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Primary | |
| 21949 |
For Research Use Only.