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CD1d Rat anti-Mouse, Functional Grade, Clone: 1B1, eBioscience™

Rat Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-0011-85

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15278327

  • 270.00€ / 500µg


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Description

Description

CD1d is a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.
Spécification

Spécification

CD1d
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P11609
AI747460, CD1.1, Cd1a, Cd1d, Ly-38, T-cell surface glycoprotein CD1d1, antigen-presenting glycoprotein CD1d1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay
1B1
Functional Grade
Cd1d1
Liquid
Cd1d1
IgG2b, kappa
500 μg
4° C
Primary
12479
Vidéos
Documents

For Research Use Only.