CD226 (DNAM-1) Rat anti-Mouse, APC, Clone: 10E5, eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 17-2261-82
Informations supplémentaires : Poids : 0.25000kg
DescriptionIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|DNAM-1, DNAM1, PTA1, TLiSA1|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.