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CD227 (Mucin 1) Monoclonal Antibody (SM3), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

195.00€ - 478.00€

Spécification

Antigen CD227 (Mucin 1)
Clone SM3
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantity Prix Quantité et disponibilité  
Code produit Marque Quantity Prix Quantité et disponibilité  
15362090
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-9893-80
25 μg
195.00€
25µg
Voir les produits de remplacement
Économisez jusqu'à 
»
Estimated Shipment: 07-05-2024
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15372090
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-9893-82
100 μg
478.00€
100µg
Voir les produits de remplacement
Économisez jusqu'à 
»
In Stock
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Description

Description

Description: This SM3 monoclonal antibody reacts with the under-glycosylated form of human Mucin 1 (MUC1, CD227), a large glycoprotein belonging to the mucin protein family. Mucin 1 contains a polypeptide core consisting of multiple tandem repeats that become highly glycosylated. Mucin 1 is typically expressed in ductal or glandular epithelial cells and is localized to the apical membrane. In cancerous cells, Mucin 1 expression is increased and membrane-specific localization is lost resulting in expression throughout the membrane and cytoplasm. High levels of under-glycosylated Mucin 1 are thought to affect cell behavior during both invasion and metastasis as well as in immune recognition. In addition, under-glycosylated Mucin 1 is shed from the epithelial cell surface and can be detected in circulation. Alterations in Mucin 1 glycosylation are found in most adenocarcinomas of the breast, lung, pancreas, prostate, and ovary. Mucin 1 has recently been shown to co-localize and interact with members of the erbB receptor kinase family, proteins that are upregulated in more aggressive forms of breast cancer. Please note this antibody sees a distinct epitope from other Mucin 1 antibodies. Applications Reported: This SM3 antibody has been reported for use in flow cytometric analysis and immunocytochemistry. Applications Tested: This SM3 antibody has been tested by flow cytometry and can be used at less than or equal to 1 μg/mL.

CD227 (Mucin 1) Monoclonal antibody specifically detects CD227 (Mucin 1) in Human samples. It is validated for Flow Cytometry, Immunocytochemistry.
Spécification

Spécification

CD227 (Mucin 1)
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen; Tumor-associated mucin
MUC1
Primary
4° C, store in dark, DO NOT FREEZE!
MUC1
SM3
Flow Cytometry, Immunocytochemistry
Alexa Fluor 488
Mouse
Human
P15941
4582
IgG1
Affinity chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications

For Research Use Only.