CD276 (B7-H3) Rat anti-Mouse, PE, Clone: M3.2D7, eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 12-5973-80
Informations supplémentaires : Poids : 0.25000kg
DescriptionA test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|PSEC0249; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; CD276 antigen; costimulatory molecule; HB7H3|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.