missing translation for 'onlineSavingsMsg'
Learn More

CD28 Syrian Hamster anti-Mouse, PE, Clone: 37.51, eBioscience™

Syrian Hamster Monoclonal Antibody

Marque:  Affymetrix eBioscience 12-0281-81

Informations supplémentaires : Poids : 0.25000kg

 Afficher plus de versions de ce produit

Code produit. 15278499

  • 88.50€ / 50µg


Date dexpédition estimée
du fournisseur 21-01-2020
Ajouter au panier

Description

Description

CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary’s Disease.
Spécification

Spécification

CD28
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P31041
MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28
Syrian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
37.51
PE
Cd28
Liquid
Cd28
IgG
50 μg
4° C, store in dark, DO NOT FREEZE!
Primary
12487
Vidéos
Documents

For Research Use Only.