CD314 (NKG2D) Rat anti-Mouse, Functional Grade, Clone: MI-6 (MI6), eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 16-5880-85
Informations supplémentaires : Poids : 0.01000kg
DescriptionPurity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
|PBS with no preservative; pH 7.2|
|CD314, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, killer cell lectin-like receptor subfamily K member 1|
|Flow Cytometry, Functional Assay, Neutralization|
For Research Use Only.