missing translation for 'onlineSavingsMsg'
Learn More

CD54 (ICAM-1) Rat anti-Mouse, Biotin, Clone: YN1/1.7.4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0541-82

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15269599

  • 132.00€ / 100µg


Estimated Shipment
14-09-2020
Add to basket

Description

Description

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
Specifications

Specifications

CD54 (ICAM-1)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P13597
BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
YN1/1.7.4
Biotin
Icam1
Liquid
Icam1
IgG2b, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
15894
Videos
Documents

For Research Use Only.