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CD8a Rat anti-Mouse, PE, Clone: 53-6.7, eBioscience™

Rat Monoclonal Antibody

52.75€ - 328.00€

Specifications

Antigen CD8a
Clone 53-6.7
Target Species Mouse
Conjugate PE
Isotype IgG2a, kappa
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Products 4
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15281009
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Affymetrix eBioscience
12-0081-81
50 μg 52.75€
50µg View alternative products
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Estimated Shipment
18-08-2020
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15278439
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Affymetrix eBioscience
12-0081-82
100 μg 79.25€
100µg View alternative products
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In stock, ready to ship: 3
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15288439
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Affymetrix eBioscience
12-0081-83
200 μg 133.00€
200µg View alternative products
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In stock, ready to ship: 1
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15298439
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Affymetrix eBioscience
12-0081-85
500 μg 328.00€
500µg View alternative products
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»
Estimated Shipment
18-08-2020
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Description

Description

CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Specifications

Specifications

CD8a
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
53-6.7
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.