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CD95 (APO-1/Fas) Mouse anti-Human, Functional Grade, Clone: EOS9.1, eBioscience™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-0958-81

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15278527

  • 89.25€ / 50µg


nous consulter 056 260 260
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Description

Description

001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.
Spécification

Spécification

CD95 (APO-1/Fas)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P25445
ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Functional Assay
EOS9.1
Functional Grade
FAS
Liquid
FAS
IgM, kappa
50 μg
4° C
Primary
355
Vidéos
Documents

For Research Use Only.