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Dexamethasone, 98%, Thermo Scientific™
1099.01€
Chemical Identifiers
| CAS | 50-02-2 |
|---|---|
| Molecular Formula | C22H29FO5 |
| Molecular Weight (g/mol) | 392.47 |
| MDL Number | MFCD00064136 |
| InChI Key | UREBDLICKHMUKA-CXSFZGCWSA-N |
| Synonym | dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol |
| PubChem CID | 5743 |
| ChEBI | CHEBI:41879 |
| IUPAC Name | (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
Description
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsAnti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
Solubility
Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.
Notes
Store in cool place. Light sensitive. Incompatible with strong oxidizing agents.
Chemical Identifiers
| 50-02-2 | |
| 392.47 | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| 5743 | |
| (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one |
| C22H29FO5 | |
| MFCD00064136 | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| CHEBI:41879 | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
Specifications
| 50-02-2 | |
| C22H29FO5 | |
| 2066651 | |
| 142943 | |
| Soluble in ethanol and dimethyl sulfoxide. Insoluble in water. | |
| +75° (c=1 in Doxane) | |
| (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one | |
| 5743 | |
| 392.47 | |
| Dexamethasone |
| 0.98 | |
| MFCD00064136 | |
| Light sensitive | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | |
| 392.47 | |
| CHEBI:41879 | |
| 98% |
Safety and Handling
Suspected of causing cancer
Carcinogenicity (category 2)
missing translation for 'einecsNumber' : 200-003-9
missing translation for 'rtecsNumber' : TU3980000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only
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