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  6. Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Product Code. 11831255 Shop All Thermo Scientific Products
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Product Code. 11831255 Supplier Thermo Scientific™ Supplier No. 21658

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Description

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Highlights:

  • Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Crosslink oriented antibodies to Protein A or G agarose
  • Immobilize proteins onto amine-coated surfaces
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-to-Amine
Cleavable No
Description Pierce DSS
Formulation Disuccinimidyl suberate; powder solid
Membrane Permeable Yes
Molecular Weight (g/mol) 368.34
PEGylated No
Sufficient For 43mL of typical 1X (1mM) reaction solution (total), or 8 separate uses
Spacer Arm Length 11.4Å
Quantity 8 x 2 mg
Solubility Not soluble in water
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For Research Use Only. Not for use in diagnostic procedures.

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