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Tango™ EDNRA-bla U2OS Cells
Tango™ EDNRA-bla U2OS Cells contain the human Endothelin Receptor A (EDNRA) linked to a TEV protease site.
Brand: Tango™ K1444
Additional Details : Weight : 0.01000kg
Description
- Gene Symbol: EDNRA
- Accession Number: NM_001957
- Tail from AVPR2 GPCR
- Population Status: Pool of Stable Cells
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
- The Tango™ EDNRA-bla U2OS cell line has been functionally validated for Z'-factor and EC50 concentrations of ET-1. The EDNRA cells have been tested for assay performance under variable assay conditions. These data are available in the Validation & Assay Performance Summary in the Manuals and Brochures section.
- Endothelin receptor type A (ENDRA) mediates signaling of endothelin proteins that regulate several critical biological processes, including development and function of blood vessels, production of certain hormones, and stimulation of cell growth and division. Defects in EDNRA-mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension, and cardiovascular disorders.
Specifications
| Transfer to liquid nitrogen immediately upon receipt or thaw for immediate use | |
| GPCRs | |
| 2 x 106 Cells |
| Fluorescent | |
| EDNRA-bla U2OS cells, EDNRA-bla U2OS Assay Protocol, Certificate of Analysis | |
| Dividing Cells |