EGFR (ErbB1) [T790M] Recombinant Human Protein, Invitrogen™
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors.
Brand: Invitrogen PV4804
Additional Details : Weight : 0.01000kg
Overexpression of EGFR has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The T790M mutant of EGFR has arisen in the clinics and displays resistance to Erlotinib (Tarceva) and Gefitinib (Iressa).
|Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.|
|EGF Receptor (ErbB) Kinase Family|
|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|
|50mM Tris pH 7.5, 150mM NaCl, 0.02% Trition X-100, 0.5mM EDTA, 2mM DTT, 50% Glycerol|
|RUO - research use only|
|EGFR (ErbB1) T790M|