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Invitrogen™ Silencer™ Select Human Ion Channel siRNA Library V4

For the first time, you can obtain the benefits of Invitrogen™Silencer™ Select siRNAs in a convenient pre-plated, library format. These siRNA collections enable medium and high throughput analysis of phenotypes resulting from inhibition of large sets of targets from specific functional classes

Brand:  Invitrogen™ 4397915

Additional Details : Weight : 0.00450kg

Product Code. 10564045

  • 10860.00€ / Each
Estimated Shipment: 19-04-2024
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Description

Description

Human Protease, Nuclear Hormone Receptor, and Ion Channel siRNA LibrariesFocused siRNA sets to human proteases, ion channels, and nuclear hormone receptors provide a cost effective means of studying these important regulators of cellular function. These siRNA libraries are each supplied in 96-well plates. The Silencer™ Select Human Protease siRNA Library V4 features 3 siRNAs per target for 494 human proteases. The Silencer™ Select Human Nuclear Hormone Receptor siRNA Library V4 includes 3 siRNAs per target for 47 nuclear hormone receptors. The Silencer™ Select Human Ion Channel siRNA Library V4 features 3 siRNAs per target for 338 human ion channels.What are Silencer™ Select siRNAs?Silencer™ Select siRNAs are the next generation Invitrogen™ siRNAs. These siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNAs with unrivalled efficacy, potency, and specificity. In siRNA screening applications, the result is fewer false negatives due to poor silencing and fewer false positives due to off target effects. In other words, with Silencer™ Select siRNAs you get cleaner, more consistent data from your primary screen, so you expend less time and resources to find true, validated targets. The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data.
  • Ready-to-ship collections of Invitrogen™ Silencer™ Select siRNAs to popular human gene classes
  • Three individual siRNAs per target provided in a convenient 96-well format
  • Designed with an all new algorithm that yields better, more consistent knockdown
  • Novel chemical modifications reduce off-target effects by up to 90%
  • Up to 100 fold more potent than currently available siRNAs
  • Demonstrated improvements in consistency and reliability of phenotypic result
Specifications

Specifications

Contains a total of 1014 unique siRNAs (0.25 nmol) targeting each of 338 human ion channel genes. Total of (12) 96-well plates: (9) plates with 88 siRNAs each. (3) plates with 74 siRNAs each. See the accompanying CD for annotation information and siRNA details. Store at or below –20 ° in a non-frost-free freezer.
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For research use only. Not for use in diagnostic procedures