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  5. Tocris Bioscience™ Eplivanserin hemifumarate

Tocris Bioscience™ Eplivanserin hemifumarate
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Product Code. 18738218
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18738218

Brand: Tocris Bioscience™ 4958/10

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Description

Potent and selective 5-HT2A antagonist

Eplivanserin hemifumarate is a potent and selective 5-HT2A antagonist (IC50 values are 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively). Attenuates cocaine-induced hyperactivity. Increases dopamine (DA) release in rat medial prefrontal cortex (mPFC); potentiates haloperidol-induced DA release in the mPFC and nucleus accumbens.
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Specifications

Chemical Name or Material (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate
CAS 130580-02-8
Synonym SR-46349 hemifumarate, SR-46349B
Quantity 10 mg
Target 5-HT2A Receptor Antagonists
Molecular Formula C19H21FN2O2.0.5C4H4O4
Formula Weight 386.42
Purity >98%
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