missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. General Cell Based Assays
  6. 10647764

Thermo Scientific™ GeneBLAzer™ PTGDR-CRE-bla CHO-K1 Cells

Product Code. 10647764
Click to view available options
Quantity:
2 x 106 Cells
Unit Size:
Each
This item is not returnable. View return policy

Product Code. 10647764

Brand: Thermo Scientific™ K1739

Please to purchase this item. Need a web account? Register with us today!

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
 View alternative products

This item is not returnable. View return policy

Description

GeneBLAzer™ PTGDR-CRE-bla CHO-K1 cells contain the human Prostanoid (PTGDR) Receptor stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ PTGDR-CRE-bla CHO-K1cells are functionally validated for Z' and EC50 concentrations of Prostaglandin D2. In addition, GeneBLAzer™ PTGDR-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The PTGDR receptor also known as DP, is a Gs-coupled receptor which activates adenylate cyclase. PTGDR receptors are located in vascular smooth muscle cells and blood platelets, and are also believed to be expressed in the brain, where they may be involved in the regulation of sleep. In addition, knockout studies in mice suggest that PTGDR may be involved in allergic and asthmatic responses. Potent agonists and antagonists for PTGDR have been identified.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_000953.2
Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage Contents:
K1739 GeneBLAzer™ PTGDR-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer™ PTGDR-CRE-bla CHO-K1 cells
• GeneBLAzer™ PTGDR-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer™ PTGDR-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol PTGDR
Population Status Single Cell Clone Origin
Product Line GeneBLAzer™
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Target Entry PTGDR
Cell Line CHO-K1
System Type GeneBLAzer™
Druggable Target GPCR
Show More Show Less

For Research Use Only. Not for use in diagnostic procedures.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.