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Tocris Bioscience™ GNE 9278
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Product Code. 18739636
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18739636

Brand: Tocris Bioscience™ 6369/10

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This item is not returnable. View return policy

Description

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

GNE 9278 is a positive allosteric modulator of NMDA receptors. Potentiates NMDA receptors containing GluN2A, 2B, 2C and 2D subunits (EC50 values are 0.74, 3.07, 0.47 and 0.32 μM in a Ca2+ influx assay, respectively). Binds within the transmembrane domain and displays preference for agonist-bound NMDA receptors. Slows receptor deactivation and enhances the potency of glutamate and glycine .
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Molecular Formula C21H27N5O3S
Formula Weight 429.54
Product Type Positive Allosteric Modulator
Purity 98%
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