missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ GNF 5837

Tocris Bioscience™ GNF 5837
GREENER_CHOICE

Product Code. 30001612
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 30001612

Brand: Tocris Bioscience™ 4559/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Potent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively). Exhibits selectivity for Trk receptors over a range of kinases, with some activity at PDGFR and c-Kit (IC50 values are 0.87 and 0.91 μM respectively). Orally bioavailable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1033769-28-6
Molecular Formula C28H21F4N5O2

Specifications

Quantity 50 mg
Formula Weight 535.49
Purity >98%
Molecular Weight (g/mol) 535.50
Chemical Name or Material GNF 5837
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.