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  5. Tocris Bioscience™ GPR52 Comp-43

Tocris Bioscience™ GPR52 Comp-43
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Product Code. 18776716
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18776716

Brand: Tocris Bioscience™ 7445/50

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Description

GPR52 receptor antagonist

GPR52 Comp-43 is a GPR52 receptor antagonist (IC50 = 0.63 μM). The use of GPR52 Comp-43 in animal models of Huntington's Disease leads to degradation and reduction of soluble and aggregated mutant huntingtin protein in the striatum. It also reduces neuronal loss, promotes neuronal survival and improves motor functions in vivo. GPR52 Comp-43 is active in vitro and brain penetrant.
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Specifications

Chemical Name or Material (2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one
CAS 1239987-91-7
Quantity 50 mg
Target Orphan 7-TM Receptor Antagonists
Molecular Formula C15H14OS
Purity 0.98
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