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Invitrogen™ Human Amyloid Precursor Protein Synthetic Peptide

Product Code. 15216279
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity unitSize
15216279 50 μg 50µg
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Product Code. 15216279 Supplier Invitrogen™ Supplier No. PEP0048

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Description

Synthetic Peptide

APP Synthetic Peptide, PEP-0048, from Invitrogen.

Amyloid Precursor Protein (APP) or Amyloid beta precursor protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. APP is important for neurite growth, neuronal adhesion and axonogenesis. APP is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms resulting from alternative splicing. Proteolytic cleavage of APP by beta- and gamma-secretases results in the generation of beta amyloid, which is the primary component of senile plaques. Senile plaques are one of the major histopathologic features of Alzheimer's disease. Abnormal regulation and processing of APP also plays a role in Down's syndrome, early onset familial Alzheimer's disease, and cerebral hemorrhage.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 351
Species Human
Purification Method purified
Accession Number P05067
Common Name Human Amyloid Precursor Protein
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol APP
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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