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Gibco™ Human CCL22 (MDC) (69 aa) Recombinant Protein, PeproTech®

Product Code. 17852123
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1 mg
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5 μg
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100µg
1mg
20µg
250µg
500µg
50µg
5µg
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Product Code. 17852123

Brand: Gibco™ 30036A1MG

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Description

Recombinant Protein

Recombinant Human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O00626
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 6367
Molecular Weight (g/mol) 8.1 kDa
Name Human CCL22 (MDC) (69 aa)
Quantity 1 mg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias A-152E5.1; Abcd1; ABCD-1; Activated B and dendritic cell-derived; AW060611; CC chemokine ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; C-C motif chemokine ligand 22; Ccl22; chemokine (C-C motif) ligand 22; DC/B-CK; DCBCK; dendritic cell and B cell derived chemokine; macrophage-derived chemokine; MDC; MDC(1-69); MDC(3-69); MDC(5-69); MDC(7-69); MGC108943; MGC34554; RP24-69A20.1; Scya22; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1
Common Name MDC
Gene Symbol CCL22
Biological Activity Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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