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Invitrogen™ Human CD27L (TNFSF7) Fc Chimera Recombinant Protein

Product Code. p-200008501
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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Product Code. 17985461

Brand: Invitrogen™ RP88013

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This item is not returnable. View return policy

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (450 μL) be added to the vial to prepare a stock solution of 2.22 mg/mL. Concentration is measured by UV.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P32970
For Use With (Application) Control, ELISA Standard, Binding Assay
Format Lyophilized
Formulation PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 970
Molecular Weight (g/mol) 45.5 kDa
Name Human CD27L (TNFSF7) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7
Common Name CD70
Gene Symbol Cd70
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His (at 2 μg/ml (100 μL/well) can bind Human CD70 hFc, the EC50 of Human CD70 hFc is 15-60 ng/mL)
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Human CD27L, amino acids Gln39-Pro193 (Accession # NP_001243.1) with an N-terminal human IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Activity Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His at 2 μg/ml (100 μL/well) can bind Human CD70 hFc, the EC50 of Human CD70 hFc is 15-60 ng/mL.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >90% as determined by SDS-PAGE.
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