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Invitrogen™ Human DOK1 Synthetic Peptide

Product Code. 15206479
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Quantity:
50 μg
Unit Size:
50µg
Product Code. Quantity unitSize
15206479 50 μg 50µg
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Product Code. 15206479

Brand: Invitrogen™ PEP0257

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This item is not returnable. View return policy

Description

Synthetic Peptide

DOK1 Synthetic Peptide, PEP-0257, from Invitrogen.

DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 1796
Species Human
Purification Method purified
Accession Number Q99704
Common Name Human DOK1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol DOK1
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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