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Invitrogen™ Human HP1 beta (aa 166-185) Control Fragment Recombinant Protein

Product Code. 30202305
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30202305

Brand: Invitrogen™ RP110054

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145003 (PA5-145003. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Spécification

Accession Number P83916
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10951
Name Human HP1 beta (aa 166-185) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias CBX; Cb x 1; Cbx-rs2; chromobox 1; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila); chromobox protein homolog 1; E430007M08Rik; heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1B; Hp1beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; M31; MOD1; modifier 1 protein; p25beta
Common Name HP1 beta
Gene Symbol CBX1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ERLTWHSYPSEDDDKKDDKN
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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