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Gibco™ Human IL-13, Animal-Free Recombinant Protein, PeproTech®

Product Code. 17843263
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Quantity:
1 mg
10 μg
100 μg
500 μg
Unit Size:
100µg
10µg
1mg
500µg
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Product Code. 17843263

Brand: Gibco™ AF20013100UG

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Description

Recombinant Protein

Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
TRUSTED_SUSTAINABILITY

Spécification

Accession Number P35225
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 3596
Molecular Weight (g/mol) 12.6 kDa
Name Human IL-13, Animal-Free
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/ μg
Gene Alias ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Common Name IL-13
Gene Symbol Il13
Biological Activity Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤1.0 ng/ml, corresponding to a specific activity of ≥1 x 10^6 units/mg
Conjugate Unconjugated
Recombinant Recombinant
Sequence MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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