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Invitrogen™ Human LILRB3 (CD85a, ILT5) Fc Chimera Recombinant Protein

Product Code. 17985591
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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Product Code. 17985591

Brand: Invitrogen™ RP88134

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This item is not returnable. View return policy

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (953 μL) be added to the vial to prepare a stock solution of 1.05 mg/mL. Concentration is measured by UV.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O75022
For Use With (Application) Control, Neutralization
Format Lyophilized
Formulation PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 11025
Molecular Weight (g/mol) 72.9 kDa
Name Human LILRB3 (CD85a, ILT5) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias CD85 antigen-like family member A; CD85A; Cell-surface glycoprotein p91; Gp91; HL9; ILT5; ILT-5; immunoglobulin-like transcript 5; leucocyte Ig-like receptor B3; leukocyte immunoglobulin like receptor B3; leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRA6; Lilrb3; LIR3; LIR-3; monocyte inhibitory receptor HL9; paired Ig-like receptor B; paired immunoglobulin-like receptor B; PIRB; PIR-B
Common Name LILRB3
Gene Symbol LILRB3
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Human LILRB3, amino acids Met1-Glu443 (Accession # AAI04994.1) with a C-terminal human IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >95% as determined by SDS-PAGE.
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