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  5. Invitrogen™ Human Notch-3 ELISA Kit

Invitrogen™ Human Notch-3 ELISA Kit

Product Code. 17164643
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Quantity:
5 x 96 Tests
96 Tests
Unit Size:
Each
Pack of 96
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Product Code. 17164643

Brand: Invitrogen™ EH346RB

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Description

ELISA

Human Notch-3 quantitates human Notch-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Notch-3.

NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; neurogenic locus notch homolog protein 3; Notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; Notch3
Assay Range 0.05 to 10 ng/mL
Assay Sensitivity 0.05 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 4854
Gene Symbol Notch3
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target NOTCH3
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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